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Save on SYMPROIC®

Commercially insured patients may pay as little as $0* for each prescription.

Save on SYMPROIC®

Commercially insured patients may pay as little as $0* for each prescription.

Collegium is dedicated to making its medications accessible to appropriate patients. Commercially insured patients may be eligible to receive savings on SYMPROIC prescriptions and may pay as little as $0 for each prescription.
Symproic savings card with Symproic logo and “pay as little at $0

*Commercially insured patients may pay as little as $0 for each prescription of SYMPROIC. Find out if you’re eligible here.

Download a SYMPROIC Copay Card

Please complete these easy steps to check your eligibility and download your copay card:

  1. Click the “Download” button to start.
  2. Print your SYMPROIC Copay Card.
  3. Present your SYMPROIC Copay Card to your pharmacist along with your prescription.
Since each SYMPROIC Copay Card contains a unique number, please do not photocopy or print multiple copies of your card.

Download

Questions about SYMPROIC cost and savings

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How much does SYMPROIC cost?

You may be able to save on opioid-induced constipation (OIC) treatment if you’re eligible. The SYMPROIC Savings Card could give you access to SYMPROIC for as little as $0. Actual savings amounts will vary based on patient insurance coverage, so it’s important for you to read and understand the eligibility requirements and terms and conditions to learn more about who can save on SYMPROIC.

What is the price of SYMPROIC with the Savings Card?

You could potentially pay $0 for SYMPROIC prescriptions when all eligibility requirements have been met. However, the specific savings on OIC treatment will vary. Call 1-855-408-8282 to learn about the SYMPROIC Savings Card and to find out whether you qualify for savings.

How does the SYMPROIC Savings Card work?

If your doctor has prescribed SYMPROIC and you've determined that you are eligible to participate in the savings card program, download your card online and present it to your pharmacist along with your prescription.

How do I activate my SYMPROIC Savings Card?

Your card will already be activated, whether you receive it from your doctor or download it online.

Eligibility Requirements

This offer is valid in the United States. Offer not valid for prescriptions reimbursed under Medicaid, a Medicare drug benefit plan, Tricare, or other federal or state health programs (such as medical assistance programs). Cash Discount Cards and other non-insurance plans are not valid as primary under this offer. If the patient is eligible for drug benefits under any such program, the patient cannot use this offer. By using this offer, the patient certifies that he or she will comply with any terms of his or her health insurance contract requiring notification to his or her payor of the existence and/or value of this offer. Offer not valid for patients under 18 years of age. It is illegal to (or offer to) sell, purchase, or trade this offer. This offer is not transferable and is limited to one offer per person. Not valid if reproduced. Void where prohibited by law. Program managed by ConnectiveRx on behalf of Collegium Pharmaceutical. The parties reserve the right to rescind, revoke, or amend this offer without notice at any time.

Terms and Conditions

Eligible patients may pay minimum of $0 and receive up to $150 off their co-pay or out-of-pocket expenses per 30-day supply of SYMPROIC® (naldemedine) capsules. Offer valid for 13 uses per year. A valid Prescriber ID# is required on the prescription.
Program managed by ConnectiveRx on behalf of Collegium Pharmaceutical. Collegium reserves the right to rescind, revoke, or amend this offer without notice at any time.
MEDICATION GUIDE

What is the most important information I should know about SYMPROIC®?

SYMPROIC may cause serious side effects, including:

  • Tear in your stomach or intestinal wall (perforation). Stomach pain that is severe can be a sign of a serious medical condition. If you get stomach pain that does not go away, stop taking SYMPROIC and get emergency medical help right away.
  • Opioid withdrawal. You may have symptoms of opioid withdrawal during treatment with SYMPROIC including sweating, chills, tearing, warm or hot feeling to your face (flush), sneezing, fever, feeling cold, abdominal pain, diarrhea, nausea, and vomiting. Tell your healthcare provider if you have any of these symptoms.

MEDICATION GUIDE

What is the most important information I should know about SYMPROIC®?

SYMPROIC may cause serious side effects, including:

  • Tear in your stomach or intestinal wall (perforation). Stomach pain that is severe can be a sign of a serious medical condition. If you get stomach pain that does not go away, stop taking SYMPROIC and get emergency medical help right away.
  • Opioid withdrawal. You may have symptoms of opioid withdrawal during treatment with SYMPROIC including sweating, chills, tearing, warm or hot feeling to your face (flush), sneezing, fever, feeling cold, abdominal pain, diarrhea, nausea, and vomiting. Tell your healthcare provider if you have any of these symptoms.

What is SYMPROIC?

SYMPROIC is a prescription medicine used to treat constipation that is caused by prescription pain medicines called opioids, in adults with long-lasting (chronic) pain that is not caused by active cancer.

It is not known if SYMPROIC is safe and effective in children.

Do not take SYMPROIC if you:

  • have a bowel blockage (intestinal obstruction) or have a history of bowel blockage.
  • are allergic to SYMPROIC or any of the ingredients in SYMPROIC. See the end of this Medication Guide for a complete list of ingredients in SYMPROIC. Tell your healthcare provider or pharmacist before you start or stop any medicines during treatment with SYMPROIC.

Before you take SYMPROIC, tell your healthcare provider about all of your medical conditions, including if you:

  • have any stomach or bowel (intestines) problems, including stomach ulcer, Crohn’s disease, diverticulitis, cancer of the stomach or bowel, or Ogilvie’s syndrome.
  • have liver problems.
  • are pregnant or plan to become pregnant. Taking SYMPROIC during pregnancy may cause opioid withdrawal symptoms in your unborn baby. Tell your healthcare provider right away if you become pregnant during treatment with SYMPROIC.
  • are breastfeeding or plan to breastfeed. It is not known if SYMPROIC passes into your breast milk. You should not breastfeed during treatment with SYMPROIC and for 3 days after your last dose. Taking SYMPROIC while you are breastfeeding may cause opioid withdrawal symptoms in your baby. You and your healthcare provider should decide if you will take SYMPROIC or breastfeed. You should not do both.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Other medicines may affect the way SYMPROIC works.

How should I take SYMPROIC?
  • Take SYMPROIC exactly as your healthcare provider tells you to take it.
  • Take your prescribed dose of SYMPROIC 1 time each day.
  • SYMPROIC can be taken with or without food.
  • SYMPROIC has been shown to be effective in people who have taken opioid pain medicines for at least 4 weeks.
  • Tell your healthcare provider if you stop taking your opioid pain medicine. If you stop taking your opioid pain medicine, you should also stop taking SYMPROIC.

What are the possible side effects of SYMPROIC?

See “What is the most important information I should know about SYMPROIC?”

The most common side effects of SYMPROIC include stomach (abdomen) pain, diarrhea, nausea and vomiting (gastroenteritis).

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of SYMPROIC. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store SYMPROIC?

  • Store SYMPROIC at room temperature between 68°F to 77°F (20°C to 25°C).
  • Keep SYMPROIC in the bottle that it comes in.

Keep SYMPROIC and all medicines out of the reach of children.

General information about the safe and effective use of SYMPROIC.

Medicines are sometimes prescribed for purposes other than those in a Medication Guide. Do not take SYMPROIC for a condition for which it was not prescribed. Do not give SYMPROIC to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information about SYMPROIC that is written for health professionals.

What are the ingredients in SYMPROIC?

Active Ingredient: naldemedine tosylate

Inactive ingredients: D-mannitol, croscarmellose sodium, magnesium stearate, hypromellose, talc, and yellow ferric oxide.

Please see full Prescribing Information and Medication Guide for SYMPROIC. Speak to your healthcare provider if you have questions about SYMPROIC.

These are not all the possible side effects of SYMPROIC. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1‑800‑FDA‑1088. For more information, go to dailymed.nlm.nih.gov.

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